VisionArray ® HPV Chip – Fast and Reliable Genotyping

The human papillomavirus (HPV) has been conclusively identified as the major risk factor for cervical cancer. It is the third most common cancer in women worldwide, with an estimated number of 530,000 new cases and 280,000 deaths each year. Over the last years the relevance of HPV in the history of oropharyngeal cancers has become more and more important which is indicated by a dramatically risen number of cancers of the oral cavity and pharynx linked to HPV. Currently more than 150 HPV types are well characterized which are classified as high-risk and low-risk types depending on the risk of progression from mild dysplasia to cancer.

VisionArray ® HPV Chips

VisionArray ® HPV Chip 1.0 - Detection of 41 HPV Types

VisionArray HPV Chip

The VisionArray HPV Chip 1.0 is intended to be used with the VisionArray Analysis Package for the qualitative detection and genotyping of PCR amplificates of 12 high-risk, 12 probably high risk, and 17 low-risk Human Papilloma Virus (HPV) genotypes that have been produced with the help of the VisionArray HPV Primer Kit and the VisionArray Detection Kit.

 

Ordering Information

Prod. No.

Tests Intended Use¹

VA-0001-10

10 CE IVD

VA-0001-50

50 CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 

Related Products

Prod. No.

Product

Tests

VS-0001-50 VisionArray HPV Set

Incl. VisionArray HPV Chip 1.0 (5x 10 pieces); VisionArray HPV Primer Kit; VisionArray Detection Kit

50
 
 

VisionArray ® HPV High Risk Chip 1.0 - Detection of 24 HPV Types

hpv highrisk chip

The VisionArray HPV High Risk Chip 1.0 is intended to be used with the VisionArray Analysis Package for the qualitative detection and genotyping of PCR amplificates of 12 high-risk and 12 probably high risk Human Papilloma Virus (HPV) genotypes that have been produced with the help of the VisionArray HPV Primer Kit and the VisionArray Detection Kit.

 

Ordering Information

Prod. No.

Tests Intended Use¹

VA-0002-10

10 CE IVD

VA-0002-50

50 CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 

Related Products

Prod. No.

Product

Tests

VS-0002-50 VisionArray HPV High Risk Set

Incl. VisionArray HPV High Risk Chip 1.0 (5x 10 pieces); VisionArray HPV Primer Kit;
VisionArray Detection Kit

50
 
 

VisionArray ® DNA Extraction, PCR, and Detection

VisionArray ® FFPE DNA Extraction Kit

FFPE DNA Extraction Kit

The VisionArray FFPE DNA Extraction Kit is designed to be used for the isolation of genomic DNA from formalin-fixed, paraffin-embeded (FFPE) specimens. The professional use of this purification system optimized for FFPE samples results in highly purified nucleic acid samples. The purified DNA can be used directly for PCR with the VisionArray HPV Primer Kit, the VisionArray PreCise Taq DNA Polymerase, and the VisionArray Uracil-DNA (UDG) Glycosylase.

 

Ordering Information

Prod. No.

Tests Intended Use

VI-0001-50

50 RUO
 

Download Information

 
 

VisionArray ® Cytology DNA Extraction Kit

Cytology DNA Extraction Kit

The VisionArray Cytology DNA Extraction Kit is designed to be used for the rapid isolation of genomic DNA from liquid-based cytology samples in order to achieve small-scale preparations of highly pure genomic DNA. The purified DNA can be used directly for PCR with the VisionArray HPV Primer Kit, the VisionArray PreCise Taq DNA Polymerase, and the VisionArray Uracil-DNA (UDG) Glycosylase.

 

Ordering Information

Prod. No.

Tests Intended Use

VI-0002-50

50 RUO
 

Download Information

 
 

VisionArray ® HPV Primer Kit

HPV Primer Kit

The VisionArray HPV Primer Kit is intended to be used for amplifying HPV types including but not limited to those detected by the VisionArray HPV Chips. During PCR, specific sections of the L1 region of the Human Papilloma Virus (HPV) will be biotinylated. The hybridization and detection of the amplified sequences is subsequently performed using the VisionArray Detection Kit and the VisionArray HPV Chip.

 

Ordering Information

Prod. No.

Tests Intended Use¹

VP-0001-50

50 CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® PreCise Taq DNA Polymerase

PreCise Taq DNA Polymerase

The VisionArray PreCise Taq DNA Polymerase is a high quality heat stable Taq polymerase intended to be used for the specific amplification of a wide range of DNA fragments. The enzyme has hot-start capabilities, reduces false positives, amplifies low-level target sequences, and promotes amplification of a variety of templates. Further on, neccessary for succesful HPV genotyping is the use of the VisionArray HPV Primer Kit in combination with the VisionArray Uracil-DNA (UDG) Glycosylase. Hybridization and detection of the amplified sequences is performed subsequently using the VisionArray Detection Kit and the VisionArray HPV Chip.

 

Ordering Information

Prod. No.

Tests Intended Use

VE-0001-100

100 CE IVD
 

Download Information

 
 

VisionArray ® Uracil-DNA Glycosylase

Uracil-DNA Glycosylase

The VisionArray Uracil-DNA (UDG) Glycosylase is an E. coli derived enzyme intended to be used to prevent carry-over contaminations from previous reactions. This is based on the principle of substituting dUTPs for dTTPs during PCR. Therefore the PCR amplificate can be "discriminated" from the initital DNA strand. Incubating the PCR mixture with the UDG enzyme at elevated temperatures under alkaline conditions (during the initial denaturation step) will remove contaminating U-DNA from the sample thereby avoiding false positive results.

 

Ordering Information

Prod. No.

Tests Intended Use

VE-0002-100

100 CE IVD
 

Download Information

 
 

VisionArray ® Detection Kit

VisionArray Detection Kit

The VisionArray Detection Kit is designed for the qualitative detection of specific DNA sequences produced with the VisionArray Primer Kit, the VisionArray PreCise Taq DNA Polymerase, the VisionArray Uracil-DNA (UDG) Glycosylase, and the corresponding VisionArray DNA Chip. The VisionArray Detection Kit contains all reagents that are required for the simple and fast hybridization and detection of PCR products on the VisionArray Chips.

 

Ordering Information

Prod. No.

Tests Intended Use¹

VK-0003-50

50 CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® Analysis Package

VisionArray Analysis Package

The VisionArray Analysis Package stands for a simple visualization and a quick analysis of the VisionArray Chip data. The analysis of a chip and the report of the results can be achieved in just a few minutes.

 

Ordering Information

Prod. No.

Intended Use¹

E-4060-1

CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® Marketing Material

 
 
 
 
 
 

 
References:
Crow JM, et al. (2012) Nature 488: S2-S3
IARC (2012) Biological Agents. IARC Monogr Eval Carcinog Risks Hum, 100B: 1-441
http://globocan.iarc.fr
 
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