PRODUCTS
VisionArray ® HPV Chip – Fast and Reliable Genotyping
The human papillomavirus (HPV) has been conclusively identified as the major risk factor for cervical cancer. It is the third most common cancer in women worldwide, with an estimated number of 530,000 new cases and 280,000 deaths each year. Over the last years the relevance of HPV in the history of oropharyngeal cancers has become more and more important which is indicated by a dramatically risen number of cancers of the oral cavity and pharynx linked to HPV. Currently more than 150 HPV types are well characterized which are classified as high-risk and low-risk types depending on the risk of progression from mild dysplasia to cancer.
VisionArray ® HPV Chips
VisionArray ® HPV Chip 1.0 - Detection of 41 HPV Types
The VisionArray HPV Chip 1.0 is intended to be used with the VisionArray Analysis Package for the qualitative detection and genotyping of PCR amplificates of 12 high-risk, 12 probably high risk, and 17 low-risk Human Papilloma Virus (HPV) genotypes that have been produced with the help of the VisionArray HPV Primer Kit and the VisionArray Detection Kit.
Ordering Information
|
Prod. No. |
Tests | Intended Use¹ |
|
VA-0001-10 |
10 |  |
|
VA-0001-50 |
50 | |
| 1 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
Download Information
Related Products
|
Prod. No. |
Product |
Tests |
| VS-0001-50 | VisionArray HPV Set |
50 |
VisionArray ® HPV High Risk Chip 1.0 - Detection of 24 HPV Types
The VisionArray HPV High Risk Chip 1.0 is intended to be used with the VisionArray Analysis Package for the qualitative detection and genotyping of PCR amplificates of 12 high-risk and 12 probably high risk Human Papilloma Virus (HPV) genotypes that have been produced with the help of the VisionArray HPV Primer Kit and the VisionArray Detection Kit.
Ordering Information
|
Prod. No. |
Tests | Intended Use¹ |
|
VA-0002-10 |
10 | |
|
VA-0002-50 |
50 | |
| 1 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
Download Information
Related Products
|
Prod. No. |
Product |
Tests |
| VS-0002-50 | VisionArray HPV High Risk Set |
50 |
VisionArray ® DNA Extraction, PCR, and Detection
VisionArray ® FFPE DNA Extraction Kit
The VisionArray FFPE DNA Extraction Kit is designed to be used for the isolation of genomic DNA from formalin-fixed, paraffin-embeded (FFPE) specimens. The professional use of this purification system optimized for FFPE samples results in highly purified nucleic acid samples. The purified DNA can be used directly for PCR with the VisionArray HPV Primer Kit, the VisionArray PreCise Taq DNA Polymerase, and the VisionArray Uracil-DNA (UDG) Glycosylase.
Ordering Information
|
Prod. No. |
Tests | Intended Use |
|
VI-0001-50 |
50 | RUO |
Download Information
VisionArray ® Cytology DNA Extraction Kit
The VisionArray Cytology DNA Extraction Kit is designed to be used for the rapid isolation of genomic DNA from liquid-based cytology samples in order to achieve small-scale preparations of highly pure genomic DNA. The purified DNA can be used directly for PCR with the VisionArray HPV Primer Kit, the VisionArray PreCise Taq DNA Polymerase, and the VisionArray Uracil-DNA (UDG) Glycosylase.
Ordering Information
|
Prod. No. |
Tests | Intended Use |
|
VI-0002-50 |
50 | RUO |
Download Information
The VisionArray HPV PreCise Master Mix is a ready to use PCR Master Mix for amplifying HPV types including but not limited to those detected by the VisionArray HPV Chips. The VisionArray PreCise Master Mix contains the HPV Primer Mix 2.0, dNTP/dUTP Solution, the VisionArray PreCise Taq DNA Polymerase, the Reaction Buffer, PreCise MgCl2 and the VisionArray Uracil-DNA Glycosylase. During PCR, specific sections of the L1 region of the Human Papilloma Virus (HPV) will be biotinylated. The hybridization and detection of the amplified sequences is subsequently performed using the VisionArray Detection Kit and the VisionArray HPV Chip.
Ordering Information
|
Prod. No. |
Tests | Intended Use¹ |
|
ES-0007-50 |
50 | |
| 1 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
Download Information
The VisionArray HPV Primer Kit 2.0 is intended to be used for amplifying HPV types including but not limited to those detected by the VisionArray HPV Chips. During PCR, specific sections of the L1 region of the Human Papilloma Virus (HPV) will be biotinylated. The hybridization and detection of the amplified sequences is subsequently performed using the VisionArray Detection Kit and the VisionArray HPV Chip. The improved VisionArray HPV Primer Kit 2.0 includes the new HPV Primer Mix 2.0 with higher sensitivity for certain HPV-types.
Ordering Information
|
Prod. No. |
Tests | Intended Use¹ |
|
VP-0001-50 |
50 | |
| 1 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
Download Information
VisionArray ® PreCise Taq DNA Polymerase
The VisionArray PreCise Taq DNA Polymerase is a high quality heat stable Taq polymerase intended to be used for the specific amplification of a wide range of DNA fragments. The enzyme has hot-start capabilities, reduces false positives, amplifies low-level target sequences, and promotes amplification of a variety of templates. Further on, neccessary for succesful HPV genotyping is the use of the VisionArray HPV Primer Kit in combination with the VisionArray Uracil-DNA (UDG) Glycosylase. Hybridization and detection of the amplified sequences is performed subsequently using the VisionArray Detection Kit and the VisionArray HPV Chip.
Ordering Information
|
Prod. No. |
Tests | Intended Use |
|
VE-0001-100 |
100 | |
Download Information
VisionArray ® Uracil-DNA Glycosylase
The VisionArray Uracil-DNA (UDG) Glycosylase is an E. coli derived enzyme intended to be used to prevent carry-over contaminations from previous reactions. This is based on the principle of substituting dUTPs for dTTPs during PCR. Therefore the PCR amplificate can be "discriminated" from the initital DNA strand. Incubating the PCR mixture with the UDG enzyme at elevated temperatures under alkaline conditions (during the initial denaturation step) will remove contaminating U-DNA from the sample thereby avoiding false positive results.
Ordering Information
|
Prod. No. |
Tests | Intended Use |
|
VE-0002-100 |
100 | |
Download Information
VisionArray ® Detection Kit
The VisionArray Detection Kit is designed for the qualitative detection of specific DNA sequences produced with the VisionArray Primer Kit, the VisionArray PreCise Taq DNA Polymerase, the VisionArray Uracil-DNA (UDG) Glycosylase, and the corresponding VisionArray DNA Chip. The VisionArray Detection Kit contains all reagents that are required for the simple and fast hybridization and detection of PCR products on the VisionArray Chips.
Ordering Information
|
Prod. No. |
Tests | Intended Use¹ |
|
VK-0003-50 |
50 | |
|
Prod. No. |
Product | |
|
E-4051-1 |
Mini Slide Centrifuge |
| 1 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
Download Information
VisionArray ® Analysis Package
The VisionArray Analysis Package stands for a simple visualization and a quick analysis of the VisionArray Chip data. The analysis of a chip and the report of the results can be achieved in just a few minutes.
Ordering Information
|
Prod. No. |
Intended Use¹ |
|
E-4060-1 |
|
| 1 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
Download Information
Crow JM, et al. (2012) Nature 488: S2-S3
IARC (2012) Biological Agents. IARC Monogr Eval Carcinog Risks Hum, 100B: 1-441
http://globocan.iarc.fr
