VisionArray ® MYCO Chip – Fast and Reliable Genotyping

The genus Mycobacterium comprises more than 140 species, which, for the purpose of diagnosis and treatment, has been grouped into three categories: M. tuberculosis complex (MTC), M. leprae, and nontuberculous mycobacteria (NTM). In the WHO European region, approximately 300,000 tuberculosis cases have been notified in 2016. The majority of the Mycobacterium species belongs to the NTM group and many of these bacteria cause life-threatening infections in humans. Pulmonary manifestations account for 80-90% of all NTM-associated diseases and the differentiation between tuberculosis pathogens and NTM is essential for diagnosis and treatment. No standard treatment of NTMs exists. Therefore, a clear distinction between the present species is of highest importance.

VisionArray ® MYCO Chips

VisionArray ® MYCO Chip 2.0

VisionArray MYCO Chip 2.0

The VisionArray MYCO Chip 2.0 is intended to be used with a VisionArray Analysis Package for the qualitative detection and identification of PCR amplicons of the genera Mycobacterium, Mycobacteriodes, Mycolicibacillus, Mycolicibacter, and Mycolicibacterium as well as several additional clinically relevant mycobacterial species that have been produced with the help of the VisionArray MYCO PreCise Master Mix 2.0.

 

Ordering Information

Prod. No.

Tests Intended Use¹

VA-0005-10

10 CE IVD

VA-0005-50

50 CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

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VisionArray ® MYCO PreCise Master Mix 2.0

PreCise Master Mix 2.0

The VisionArray MYCO PreCise Master Mix 2.0 is a ready to use PCR Master Mix for amplifying ITS and, in case of M. tuberculosis complex, IS6110 region of mycobacterial genomes including but not limited to those detected by the VisionArray MYCO Chip 2.0. The VisionArray MYCO PreCise Master Mix 2.0 contains the VisionArray MYCO Primer Mix 2.0, dNTP/dUTP Solution, the VisionArray PreCise Taq DNA Polymerase, the PCR-Buffer, MgCl2, and the VisionArray Uracil-DNA Glycosylase. During PCR, specific sections of the ITS and IS6110 region of the mycobacterial genomes will be biotinylated. The hybridization and detection of the amplified sequences is subsequently performed using the VisionArray Detection Kit and the VisionArray MYCO Chip 2.0.

 

Ordering Information

Prod. No.

Tests Intended Use¹

ES-0008-50

50 CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray® MYCO Sequencing Primers

MYCO Sequencing Primers

The VisionArray Sequencing Primers are intended to be used for further characterization of Mycobacteria specific sequences from VisionArray PCR products. The PCR product obtained from the VisionArray MYCO PreCise Master Mix 2.0 serves as template in a nested re-amplification of the mycobacterial ITS region in combination with a Taq Polymerase. The PCR product obtained can then be analyzed in a subsequent sequencing reaction by appropriate providers and further characterized using BLAST or other sequence analysis software.

 

Ordering Information

Prod. No.

Tests Intended Use

PR-0003-50

50 RUO
 

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VisionArray ® Detection Kit

VisionArray Detection Kit

The VisionArray Detection Kit is designed for the qualitative detection of specific DNA sequences produced with the VisionArray MYCO PreCise Master Mix 2.0 and the corresponding VisionArray MYCO Chip 2.0. The VisionArray Detection Kit contains all reagents that are required for the simple and fast hybridization and detection of PCR products on the VisionArray MYCO Chip 2.0.

 

Ordering Information

Prod. No.

Tests Intended Use¹

VK-0003-50

50 CE IVD

 

Prod. No.

Product

E-4051-1

Mini Slide Centrifuge  

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

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VisionArray ® Analysis Packages

VisionArray ® Analysis Package MultiScan

VisionArray Analysis Package MultiScan

The VisionArray Analysis Package MultiScan stands for a simple visualization and quick analysis of up to six VisionArray Chips in a single run. The VisionArray Analyzer Software MultiScan can thereby analyze HPV and MYCO specific Chips simultaneously. Only a few minutes will pass from scan to report.

 

Ordering Information

Prod. No.

Intended Use¹

E-4070-1

CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® Analysis Package SingleScan

VisionArray Analysis Package SingleScan

The VisionArray Analysis Package SingleScan stands for a simple visualization and a quick analysis of the VisionArray Chip data. The analysis of a chip and the report of the results can be achieved in just a few minutes.

 

Ordering Information

Prod. No.

Intended Use¹

E-4060-1

CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® Marketing Materials

 
 
 
 
 
 

 
References:
Griffith DE, et al. (2007) Am J Respir Crit Core Med 175: 367-416.
Gupta RS, et al. (2018) Front Microbiol 9: 67.
Oren A & Carrity GM (2019) Int J Syst Evol Microbiol 69: 597-9.
Perez-Martinez I, et al. (2013) BMC Res Notes 6: 531.
Simons S, et al. (2011) Emerg Infect Dis 17: 343-9.
Tortoli E (2009) Clin Microbiol Infect 15: 906-10.
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