PRODUCTS
ZytoLight ® SPEC MYB/CEN 6 Dual Color Probe
The ZytoLight SPEC MYB/CEN 6 Dual Color Probe is designed to detect deletions affecting the chromosomal region 6q23.3 harboring the MYB gene. 3-10% of cronic lymphocytic leukemia (CLL) cases have been shown to harbor structural aberrations in the chromosomal region of 6q, one of them is 6q23.
Probe Maps
Ordering Information
| Prod. No.: | Tests¹ (Volume): | Intended Use²: | ||
|---|---|---|---|---|
| Z-2281-50 |
|
 |
Download Information
| 1 | Using 10 μl probe solution per test. |
| 2 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
is designed to detect inversions involving the chromosomal region 2p23.1-p23.2 harboring the ALK gene and the chromosomal region 2p21 harboring the EML4 gene. Moreover, using this probe it is possible to discriminate between EML4-ALK inversions and translocations affecting ALK, but not EML4.
ALK kinase targeted therapies may represent a very effective therapeutic strategy in NSCLC patients carrying EML4-ALK rearrangements.
