ZytoLight ® SPEC NUP214 Dual Color Break Apart Probe
The ZytoLight SPEC NUP214 Dual Color Break Apart Probe is designed for the detection of translocations involving the chromosomal region 9q34.13 harboring the NUP214 gene. Rearrangements of the NUP214 gene have been implicated in the pathogenesis of several types of hematologic malignancies, including T-cell acute lymphoblastic leukaemia (T-ALL), acute myeloid leukemia (AML), and also myelodysplastic syndrome (MDS).
Malignancies with NUP214 rearrangements are associated with a poor prognosis indicating the usefulness of NUP214 also as a prognostic biomarker.
|Prod. No.:||Tests¹ (Volume):||Intended Use²:|
|1||Using 10 μl probe solution per test.|
|2||CE IVD only available in certain countries. All other countries research use only!
Please contact your local dealer for more information.