ZytoLight ® SPEC PDGFRA/FIP1L1 TriCheckTM Probe

The ZytoLight ® SPEC PDGFRA/FIP1L1 TriCheckTM Probe is designed to detect rearrangements involving the PDGFRA gene. PDGFRA gene rearrangements most frequently occur in chronic eosinophilic leukemia (CEL), but can be also detected in AML, and T-ALL. The most common gene fusion is FIP1L1-PDGFRA caused by an 800 kb interstitial deletion on chromosome 4q12. Five other partner genes have been identified, including BCR, ETV6, KIF5B, STRN, and CDK5RAP2.
Identification of patients harboring a PDGFRA rearrangement is important as these patients respond to a targeted therapy with imatinib. Hence, detection of PDGFRA rearrangements by FISH may be of diagnostic and predictive relevance.

Probe Maps


Ordering Information

Prod. No.:Tests¹ (Volume):Registration Status²:
5 (50 μl)

Download Information


1 Using 10 μl probe solution per test.
2 In vitro diagnostic medical device according to EU directive 98/79/EC. 
CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

ISO 9001
ISO 13485
ZytoVision GmbH


For ZytoVision products additional information is available, which is only valid outside the United States of America (USA). With this action you confirm that you have read this legal notice, that you agree with the terms of use, and that you are not intending to use the information provided on this website within USA.

Accept & Continue