PRODUCTS
ZytoLight ® SPEC IRF4,DUSP22 Dual Color Break Apart Probe
The ZytoLight ® SPEC IRF4,DUSP22 Dual Color Break Apart Probe is designed to detect translocations involving the DUSP22 and IRF4 genes. Rearrangements of the IRF4/DUSP22 chromosomal region have been detected in various B-cell and T-cell lymphomas.
Large B-cell lymphoma (LBCL) with IRF4 rearrangement is considered a distinct new provisional entity. Most cases have IG/IRF4 fusions and have a favorable prognosis. Moreover, IRF4 translocation has a high specificity for cutaneous cutaneous anaplastic large cell lymphoma (ALCL) supporting the clinical utility of FISH for IRF4 in the differential diagnosis of T-cell lymphoproliferative disorders.
Probe Maps
Ordering Information
| Prod. No.: | Tests¹ (Volume): | Intended Use²: | ||
|---|---|---|---|---|
| Z-2210-50 |
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Download Information
| 1 | Using 10 μl probe solution per test. |
| 2 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
