ZytoLight ® SPEC IRF4,DUSP22 Dual Color Break Apart Probe

The ZytoLight ® SPEC IRF4,DUSP22 Dual Color Break Apart Probe is designed to detect translocations involving the DUSP22 and IRF4 genes. Rearrangements of the IRF4/DUSP22 chromosomal region have been detected in various B-cell and T-cell lymphomas.
Large B-cell lymphoma (LBCL) with IRF4 rearrangement is considered a distinct new provisional entity. Most cases have IG/IRF4 fusions and have a favorable prognosis. Moreover, IRF4 translocation has a high specificity for cutaneous cutaneous anaplastic large cell lymphoma (ALCL) supporting the clinical utility of FISH for IRF4 in the differential diagnosis of T-cell lymphoproliferative disorders.

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Ordering Information

Prod. No.:Tests¹ (Volume):Registration Status²:
5 (50 μl)

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1 Using 10 μl probe solution per test.
2 In vitro diagnostic medical device according to EU directive 98/79/EC. 
CE IVD only available in certain countries. All other countries research use only! 
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