PRODUCTS
ZytoDot ® 2C SPEC NTRK1 Break Apart Probe
The ZytoDot ® 2C SPEC NTRK1 Break Apart Probe is desgined to detect translocations involving the chromosomal region 1q23.1 harboring the NTRK1 gene. More than 40 different 5' gene partners of NTRK1 have been described in a diverse range of tumor types including, e.g., papillary thyroid carcinoma, lung cancer, sarcomas, and spitzoid neoplasms. The treatment of patients with NTRK1, 2, or 3 fusion-positive cancers with an NTRK inhibitor, such as the FDA-approved drugs larotrectinib or entrectinib, is associated with high response rates, regardless of NTRK gene, fusion partner, and tumor type.
Probe Maps
Ordering Information
| Prod. No.: | Tests¹ (Volume): | Registration Status²: | ||
|---|---|---|---|---|
| C-3078-100 |
|
 |
Download Information
| 1 | Using 10 μl probe solution per test. |
| 2 | In vitro diagnostic medical device according to EU directive 98/79/EC. CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
